SINGLE STRANDED DNA BINDING

Preparation of Human Mitochondrial Single-Stranded DNA-Binding Protein

for understanding the origins of mitochondrial disease. Mitochondrial single-stranded DNA-binding protein (mtSSB) is an essential component of the mtDNA replication machinery. To facilitate ongoing biochemical studies, a recombinant source of mtSSB is needed

Expression, Purification, and In Vitro Assays of Mitochondrial Single-Stranded DNA-Binding Protein

The mitochondrial single-stranded DNA-binding protein (mtSSB) is encoded by a single-copy nuclear gene in mammals. After de novo synthesis in the cytosol, mtSSB is transported into mitochondria, where it participates in mitochondrial DNA

单链DNA single－stranded DNA

　　大部分 DNA以双螺旋结构存在，但一经热或碱处理就会变为单链状态。单链 DNA就是指以这种状态存在的 DNA。单链 DNA在分子流体力学性质、吸收光谱、碱基反应性质等方面都和双链 DNA不同。某些噬菌体粒子内含有单链环状的 DNA，这样的噬菌体 DNA在细胞内增殖时则形成双链 DNA。