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文献和实验Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization
(2 ,3 ). To identify DNA sequences encoding the corresponding full-length protein necessary to verify NPY receptor activity, we chose to clone the human genomic DNA (4 ). This approach offers a number of advantages over cDNA library screening, especially
In Vitro Development of Human KillerImmunoglobulin Receptor-Positive NK Cells
The in vitro culture system outlined in this chapter allows for the delineation of events that occur during the development of CD34+ hematopoietic precursor cells into mature KIR+ human NK cells. This system can also be utilized to study
Studies on Androgen Receptor Mutations and Amplification in Human Prostate Cancer
Prostate cancer is a heterogenous neoplasm that is palliatively treated with androgen ablation therapy. Endocrine therapy aims to block the androgen receptor (AR), which has a central role in the transmission of extracellular signals
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