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文献和实验The severe combined immune deficient human (SCID-hu) myeloma model is the only available model in which primary myeloma cells grow in vivo in a human bone marrow microenvironment. A SCID mouse receives an implanted human fetal bone
response may follow the transfusion of serum proteins between humans, but a vigorous immune response (serum sickness) commonly follows transfusion of horse serum proteins to a human the host's genetic makeup, especially the MHC
The Mouse as Model System to Study Host‐Pathogen Interactions in Influenza A Infections
., Palese, P., Taubenberger, J.K., Garcia‐Sastre, A., Swayne, D.E., and Katze, M.G. 2006. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature 443:578‐581.
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