- ￥1024 - 1824
- 正能
- 690296
- 2026年03月05日
- IHC-P
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
IHC-P
- 适应物种：
Human,Mouse,Rat
- 标记物：
Unconjugated
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 形态：
liquid
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1024.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1824.0 |
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
of the serine/threonine kinaseAkt, which will phosphorylate GSK-3 at specific serine residues(Ser21 in GSK-3a and Ser9 in GSK-3b), leading to the inactivationof GSK-3 kinase activity (10) . However, this phosphorylationand inactivation of GSK-3 by Akt
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