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北京柏瑞图科技有限公司
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文献和实验Methods for Adeno-Associated Virus-Mediated Gene Transfer into Muscle
(7 ,8 ). In this chapter, we describe how to produce rAAV free of wild-type adenovirus. In addition, Summerford and Samulski (9 ) recently identified the receptor for AAV, heparan sulfate proteoglycan.
_CHICK Glypican-1 precursor (heparan sulfate proteoglycan core protein). P50593 550 AA. LAMP_CHICK Limbic system-associated membrane protein precursor (e19s). Q98919 338 AA. CADD_CHICK T-Cadherin precursor (truncated-cadherin) (cadherin-13).712 AA. P
, for example, heparan sulfate [11,12]. However, not all known CPPs are rich in arginine residues (Table 1) and different peptides could use different pathways for uptake. In addition, the mechanism of translocation could be dependent on whether it is the free
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