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文献和实验The Major Histocompatibility Complex: A Paradigm for Studies of the Human Genome
The major histocompatibility complex (MHC) on chromosome 6 is one of the most intensively studied regions of the human genome and has many features which make it unique. It is the source of much research interest because of its role
Quantitation of Major Histocompatibility Complex Antigen Endocytosis Using Capture ELISA
Major histocompatibility class I and II (MHC-I and MHC-II) antigens (Ags), as well as a variety of cell surface receptors, have been shown to enter the endocytic pathway of antigen-presenting cells (APCs). MHC Ags endocytose into clathrin
人白细胞抗原(human leukocyte antigen,HLA)
相容性抗原分为“主要组织相容性抗原系统”(major histocompatibility antigen system)和“次要组织相容性系统”(minor histocompatibility antigen system)。前者指体细胞表面抗原能引起受体淋巴细胞强应答,产生强烈排斥反应;后者指引起弱应答和弱排斥反应。主要组织相容性抗原是一组抗原,由一组连锁基因编码。这组基因称为主要组织相容性复合体基因(major histocompatibility complex gene,MHC
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