SGTA

产品英文名称：
Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha

英文简称:
SGTA

中文名称:
重组人小谷氨酰胺三角四肽重复区蛋白α

背景资料:
SGTA is a ubiquitously expressed protein that contains thrSGTA Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 321 amino acids （1-313 a.a.） and having a molecular mass of 35.1 kDa. SGTA protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography. TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor （AR）-chaperone-cochaperone complex， functions as a cochaperone and participates in androgen signaling. SGTA acts as a cochaperone that binds directly to HSC70 and HSP70 and mediatess their ATPase activity. While being involved in apoptosis and androgen signaling， SGTA is a possible molecule for polycystic ovary syndrome， a disorder characterized by androgen excess， obesity and menstrual disturbances.

产品描述:
SGTA Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 321 amino acids （1-313 a.a.） and having a molecular mass of 35.1 kDa. SGTA protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
来源宿主:
大肠杆菌中重组表达

序列:
MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQELEHHHHH H.

溶解建议:
Sterile filtered colorless solution. SGTA Human solution containing 20mM Trsi HCL pH-8， 1mM DTT and 10% glycerol.

保存建议：
SGTA human although stable at 4℃ for 1 week， should be stored desiccated below -18℃. Please prevent freeze thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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