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文献和实验Immunohistochemistry in Leukemias and Lymphomas
, in the absence of CD45 ( see Fig. 1 ). Additional examples are mantle cell lymphoma with its unique nuclear expression of cyclin D1, and hairy cell leukemia, characterized by coexpression of CD22 and CD1 1c, a monocytoid marker. Beyond its diagnostic
proliferation Associated with CD5 Positive staining (normal): B cells Positive staining (disease): hairy cell leukemia
CD85/CD85a/CD85b/CD85c/CD85d/CD85e/CD85f分子
Summary: Marker of plasma cells and hairy cell leukemia Aka LILRB1 ILT/LIR family Inhibitory MHC class I receptor prevents killing by NK and T cells Also inhibits B cells activated by antigen receptor and myelomonocytic cells
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