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文献和实验and disease. Keywords: agonist; antagonist allosteric modulator; G protein?coupled receptor; heterotrimeric G protein; ion channels; ligand; new chemical entity (NCE); orphan receptor; structure activity relationship (SAR
Practical Aspects of Radioligand Binding
The Scatchard (Rosenthal) plot. The specific bound ( B ) is plotted on the x axis, and the ratio of specific bound to free ( B / F ) is plotted on the y axis. The x intercept is the maximal amount of specific binding ( B max ). The slope of the plot
: Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T (2003). "A uniform system for microRNA annotation". RNA 9 (3): 277–279. doi:10.1261/rna.2183803. PMC 1370393
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