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苏州瑞诺德生物科技有限公司
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文献和实验Anti-c-erb-B-2 Ribozyme for Breast Cancer
Our laboratory has investigated the cleavage activity of an-anti-c-erb -B-2 ribozyme. The c-erb -B-2 proto-oncogene (also called HER-2/neu ) encodes a 185 kDa transmembrane tyrosine kinase-type receptor that is homologous with the epidermal
Anti-c-erb1B2 Ribozyme for Gene Therapy of Breast Cancer
The application of antioncogene ribozyme in the gene therapy of breast cancer by means of recombinant adenoviral vector is dicussed in this chapter. We have shown that recombinant adenovirus encoding anti-cerbB2 ribozyme inhibited the breast
Interfering with Ras Signaling Using Membrane-Permeable Peptides or Drugs
During the last two decades since the first oncogene product called v-Src was identified as a constitutively activated mutant of a normal mitogenic gene (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly
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