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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
- 适应物种:
Human
- 保质期:
12个月
- 库存:
现货
- 宿主:
Rabbit
- 应用范围:
WB,FC,IP
- 靶点:
IL 1 Receptor Accessory Protein
- 规格:
20μL/50μL/100μL
| 规格: | 20μL | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 50μL | 产品价格: | ¥1000.0 |
| 规格: | 100μL | 产品价格: | ¥1800.0 |
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文献和实验Overview of Receptor Allosterism
, which recognizes endogenous ligands, most G protein?coupled receptors (GPCRs) possess topographically distinct allosteric sites that can be recognized by small molecules and accessory cellular proteins. Ligand binding to allosteric sites promotes a conformational
, inhibitor of NFκ B; IRAK, IL-1R-associated kinase; LTA, lipoteichoic acid; NIK, NFκ B-inducing kinase; PGN, peptidoglycan; RIP, receptor-interacting protein; TNF, tumour necrosis factor; TNFR, TNF receptor; TRADD, TNFR1-associated protein with death domain
, as well as SIGIRR, which interferes with intracellular ST2L signaling. Abbreviations: GAB2, GRB2-associated-binding protein 2; IL, interleukin; IL-1RAcP, IL-1 receptor accessory protein; IRAK, IL-1 receptor-associated kinase; ITAM, immunoreceptor tyrosine-based
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