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Cytochrome P450 3A5 (DGR18902)

Rabbit mAb
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  • ¥398
  • 戴格
  • 浙江杭州
  • db14612
  • 2026年02月03日
  • WB, IHC-P, IP
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      A synthetic peptide of human Cytochrome P450 3A5

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

    • 克隆性

      Monoclonal

    • 适应物种

      Human

    • 库存

      99

    • 宿主

      Rabbit

    • 应用范围

      WB, IHC-P, IP

    • 靶点

      Cytochrome P450 3A5

    • 规格

      10μl

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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    图标文献和实验
    相关实验
    • Genotyping for Cytochrome P450 Polymorphisms

      Protocols for the extraction of DNA from human blood and for genotyping for a number of common cytochrome P450 polymorphisms using either polymerase chain reaction (PCR)-restriction fragment length polymorphism or PCR-single-strand

    • Isolation and Purification of Constitutive Forms of Microsomal Cytochrome P450

      from microsomes through the use of proteases were not successful, resulting merely in the solubilization of a number of other microsomal proteins. The breakthrough event was the solubrlizatron of rabbit liver microsomal cytochrome P450 using the ionic detergent

    • Monoclonal Antibodies to Cytochromes P450

      specifically recognizes a single antigenic determinant or “epltope” on the protein antigen, which, in our studies, is a specific individual cytochrome P450 (P450). This specificity of the MAb continues for the lifetime of the hybridoma cell, which can be frozen

    图标技术资料

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