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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Recombinant Mouse ST6GALNAC2
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥840.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2520.0 |
| 规格: | 500ug | 产品价格: | 询价 |
| 规格: | 1mg | 产品价格: | 询价 |
Recombinant Mouse ST6GALNAC2 (CB51)
产品说明(Description)
Recombinant Mouse Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus.
Accession #: P70277
Known as: Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase,GalNAc alpha-2,6-sialyltransferase II,ST6GalNAc II,Sialyltransferase 7B,SIAT7-B
制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 50mMTris,150mMNaCl,pH7.5.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输(Shipping)
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景(Background)
Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type?II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.?it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY
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文献和实验with a Ca2+ -free medium or with trypsin/dispase. The latter facilitates the introduction of recombinant or trappable probes and microimaging studies of, for example, changes in cytosolic-free Ca2+ concentration or the dynamics of individual organelles
Purification of Recombinant Poly(ADP-Ribose) Polymerases
, more than 11 mg of pure and highly active mouse PARP-2 can be obtained from 1 L of Sf9 insect cell culture.
PRIMARY MOUSE KERATINOCYTE CULTURES Isolation of epidermal keratinocytes from neonatal mice is based on the protocol of Dlugosz et al., Methods Enzymol . 254:3-20 (1995). The epidermis from a newborn mouse should yield
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