- ￥640 - 1752
- 近岸蛋白(Novoprotein)
- 中国
- C256
- 2026年01月30日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human HRSP12/Heat-Responsive Protein 12
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥640.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥1752.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human HRSP12/Heat-Responsive Protein 12 (C256)
产品说明(Description)
Recombinant Human Heat-Responsive Protein 12 is produced by our E.coli expression system and the target gene encoding Met1-Leu137 is expressed with a 6His tag at the N-terminus.
Accession #: P52758
Known as: Ribonuclease UK114; 14.5 kDa Translational Inhibitor Protein; p14.5; Heat-Responsive Protein 12; UK114 Antigen Homolog; HRSP12; PSP
制剂（Formulation）
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输（Shipping）
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存（Storage）
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景（Background）
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY
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