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Biotinylated Recombinant Human

PCSK9 (C-Avi)
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  • ¥2300 - 6210
  • 近岸蛋白(Novoprotein)已认证
  • 中国
  • CA84
  • 2026年01月30日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      Biotinylated Recombinant Human PCSK9 (C-Avi)

    • 规格

      20ug/100ug

    规格:20ug产品价格:¥2300.0
    规格:100ug产品价格:¥6210.0

    Biotinylated Recombinant Human PCSK9 (C-Avi)  (CA84)

     

    产品说明(Description)

    Biotinylated Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9 is produced by ourMammalian expression system and the target gene encoding Gln31-Gln692(Val474Ile,Gly670Glu) isexpressed with a Avi tag at the C-terminus.

    Accession #: Q8NBP7

    Known as: Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1

     

    制剂(Formulation)

    Supplied as a 0.2 μm filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4.

     

    质量控制(Quality Control) 

     

    Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

    Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

    Biotin:Protein Ratio        The biotin to protein ratio is 0.5-1 as determined by the HABA assay.

     

     

    运输(Shipping)

    The product is shipped on dry ice/polar packs. 
    Upon receipt, store it immediately at the temperature listed below.

     

    保存(Storage)

    Store at ≤-70°C, stable for 6 months after receipt.
    Store at ≤-70°C, stable for 3 months under sterile conditions after opening. 
    Please minimize freeze-thaw cycles.     

     

    背景(Background)

    Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

     

    电泳(SDS-PAGE)

     

    FOR RESEARCH USE ONLY

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