Recombinant Human GSTP1/Glutat

Recombinant Human GSTP1/Glutathione S-transferase P  (CK07)

产品说明(Description)

Recombinant Human Glutathione S-Transferase Pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Gln210 is expressed. 

Accession #: AAH10915.1

Known as: Glutathione S-transferase P;GSTP1;GST class-pi;GSTP1-1;FAEES3;GST3;

 

制剂(Formulation)

Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,10% Glycerol,pH 8.0.

 

质量控制(Quality Control) 

 

Purity:        Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

 

 

运输(Shipping)

The product is shipped on dry ice/polar packs. 
Upon receipt, store it immediately at the temperature listed below.

 

保存(Storage)

Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening. 
Please minimize freeze-thaw cycles.     

 

背景(Background)

Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain.  GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta.  The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

 

电泳(SDS-PAGE)

 

FOR RESEARCH USE ONLY