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ATM KINASE, PSER1981, MSX-100UG
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文献和实验Identifying Inhibitors of ATM and ATR Kinase Activities
The Ataxia Telangiectasia mutated (ATM) and the ATM and Rad3-related (ATR) proteins function in partially overlapping DNA damage checkpoint pathways that orchestrate the cellular response to DNA damage. Both proteins belong to a growing
Analyzing the Regulation and Function of ATM
transfected cell line. ATM protein induction is monitored by immunoblotting with antibodies against both ATM and a FLAG sequence tag in the recombinant protein. Extracts from irradiated cells are immunoprecipitated with anti-ATM antibodies, and protein kinase
Detecting ATM-Dependent Chromatin Modification in DNA Damage and Heat Shock Response
The ataxia telangiectasia-mutated gene product (ATM), whose loss of function is responsible for ataxia telangiectasia (A-T), is a protein kinase that interacts with several substrates and is implicated in mitogenic signal transduction
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