- 询价
- Nebulabio
- 中国
- NBAB-191522
- 2026年01月05日
- ELISA, WB
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Insulin Receptor β protein
- 形态：
liquid
- 克隆性：
单克隆
- 保质期：
见COA
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 应用范围：
ELISA, WB
- 靶点：
Insulin Receptor β
- 抗体英文名：
Anti-Insulin Receptor β Monoclonal Antibody
- 抗体名：
抗Insulin Receptor β单抗
- 规格：
100ul; 500ul; 1ml
| 产品信息
品名：NebuSelect™ Anti-Insulin Receptor β Monoclonal Antibody
别名：Insulin receptor, IR, CD antigen CD220, [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]
货号：NBAB-191522
品牌：Nebulabio
规格：100ul; 500ul; 1ml
| 产品描述
NebuSelect™ Anti-Insulin Receptor β Monoclonal Antibody (Cat# NBAB-191522) was produced in rabbits immunized with recombinant Human Insulin Receptor β protein, and it reacts with Human, Mouse, Rat. This antibody is validated for ELISA, WB.
| 产品属性
Product Category：Rabbit MAb
Reactivity：Human, Mouse, Rat
Specificity：Human Insulin Receptor β
Immunogen：Recombinant Human Insulin Receptor β protein
Isotype：Monoclonal Rabbit IgG
Purification：Protein A & Protein G Affinity Purification
Buffer：0.2 μm filtered solution in PBS, pH7.4, containing 0.09% Sodium azide, 50% glycerol.
Conjugate：Unconjugated
Applications：ELISA, WB
Dilution：ELISA 1:2000～1:10000; WB: 1:1000～1:5000
Storage：This liquid antibody can be stored at 2℃-8℃ for at least two weeks. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or antibody diluent, the antibody is stable for at least two weeks at 2-4℃.
For Research Use Only!
To get more information, please contact us freely.
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文献和实验胰岛素受体是一个四聚体，由两个α亚基和两个β亚基通过二硫键连接。两个α亚基位于细胞质膜的外侧，其上有胰岛素的结合位点；两个β亚基是跨膜蛋白，起信号转导作用。无胰岛素结合时，受体的酪氨酸蛋白激酶没有活性。当胰岛素与受体的α亚基结合并改变了β亚基的构型后，酪氨酸蛋白激酶才被激活，激活后可催化两个反应∶①使四聚体复合物中β亚基特异位点的酪氨酸残基磷酸化,这种过程称为自我磷酸化(autophosphorylation)；②将胰岛素受体底物(insulin receptor substrate
Detection of Insulin Production by Immunohistochemistry
), and these allow sensitive and specific detection of even very low levels of expression. Described below is the protocol for detection of insulin in β-cell lines in culture, using a FITC-coupled secondary antibody. A broad range of secondary antibodies
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receptor-mediated transcytosis or transport (RMT) across the BBB in vivo. Certain peptidomimetic monoclonal antibodies (mAb) for insulin receptor or transferrin receptor can also cross the BBB via RMT on the endogenous receptors. These mAb can act
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