IFN-γ 重组小鼠干扰素γ 小鼠重组蛋白 细胞因子

Mouse IFN-γ Protein (PRP1961)

重组小鼠干扰素γ（Mouse IFN-γ Protein）是一种高纯度、高活性的细胞因子，适用于多种细胞水平的科学研究应用。本品通过大肠杆菌表达系统重组表达，无标签干扰，严格质控，确保批次间一致性，为免疫学、肿瘤学及病毒感染机制研究提供可靠工具。

产品特性

• 来源：小鼠
• 表达宿主：大肠杆菌
• 产品形式：冻干粉
• 纯度：> 95%（SDS-PAGE检测）
• 分子量：约 16.9 kDa
• 活性：经L929细胞增殖实验测定，ED₅₀ 通常为 0.03 ng/mL，比活性 >3.33 × 10⁷ IU/mg
• 保存建议：-20°C 避光保存，有效期12个月

生物学背景

IFN-γ（干扰素γ）属于II型干扰素家族，主要由NK细胞、NKT细胞及CD4⁺/CD8⁺ T细胞分泌，在先天性和适应性免疫应答中发挥核心作用。它具有抗病毒、免疫调节和抗肿瘤等多种生物学功能，可激活巨噬细胞、增强NK细胞活性，并对转化细胞表现出抗增殖作用。IFN-γ在病毒感染、细胞内细菌感染和肿瘤免疫中具有关键作用，其异常表达也与某些自身免疫性疾病相关。

应用领域

• 免疫细胞活化与功能研究
• 巨噬细胞极化和抗原提呈实验
• 病毒免疫应答机制分析
• 肿瘤免疫微环境模型构建

规格与价格

规格	价格（元）	货期
20 µg	520	现货，次日发货
100 µg	1498	现货，次日发货
500 µg	3398	现货，次日发货
1 mg	请咨询	请咨询

使用说明

本品为冻干粉形式，建议在无菌条件下复溶后使用，避免反复冻融。具体复溶浓度及培养条件请根据实验体系优化。

注意事项

• 本品仅供研究使用，不适用于人体或临床诊断。
• 使用前请阅读相关文献并了解所在地区的专利许可情况。
• 操作时请遵守生物安全相关规定。

运输条件：冰袋运输（蓝冰）

基因ID：15978 | UniProt ID：P01580

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Mouse IFN-γ Protein (PRP1961)

Recombinant mouse interferon‑γ (Mouse IFN‑γ Protein) is a high‑purity, high‑activity cytokine suitable for a broad range of cellular‑level scientific research applications. This product is expressed via an Escherichia coli recombinant system, tag‑free, with stringent quality control to ensure batch‑to‑batch consistency, providing a reliable tool for immunology, oncology, and viral infection mechanism studies.

Product Characteristics

• Source: Mouse
• Expression Host: Escherichia coli
• Product Form: Lyophilized powder
• Purity: >95% (SDS‑PAGE analysis)
• Molecular Weight: Approximately 16.9 kDa
• Activity: Determined by L929 cell proliferation assay; typical ED₅₀ = 0.03 ng/mL, specific activity > 3.33 × 10⁷ IU/mg
• Storage Recommendation: Store at –20 °C, protected from light; shelf life 12 months

Biological Background

IFN‑γ (interferon‑γ) belongs to the type II interferon family and is primarily secreted by NK cells, NKT cells, and CD4⁺/CD8⁺ T cells. It plays a central role in innate and adaptive immune responses, exhibiting antiviral, immunoregulatory, and antitumor activities. IFN‑γ activates macrophages, enhances NK cell cytotoxicity, and exerts antiproliferative effects on transformed cells. It is pivotal in viral infections, intracellular bacterial infections, and tumor immunity, while dysregulated expression is associated with certain autoimmune diseases.

Application Areas

• Immune cell activation and functional studies
• Macrophage polarization and antigen‑presentation assays
• Analysis of antiviral immune response mechanisms
• Construction of tumor immune microenvironment models

Specifications and Pricing

Specification	Price (CNY)	Lead Time
20 µg	520	In stock, next‑day shipment
100 µg	1498	In stock, next‑day shipment
500 µg	3398	In stock, next‑day shipment
1 mg	Please inquire	Please inquire

Usage Instructions

The product is supplied as a lyophilized powder; reconstitute under sterile conditions and avoid repeated freeze‑thaw cycles. Optimize reconstitution concentration and culture conditions according to your specific experimental system.

Precautions

• This product is for research use only and is not intended for human or clinical diagnostic applications.
• Review relevant literature and verify any patent licensing requirements in your jurisdiction before use.
• Follow all applicable biosafety regulations during handling.

Shipping Conditions: Ice pack (blue ice) transport

Gene ID: 15978 | UniProt ID: P01580

Note: The above information may change due to product optimization or upgrades; please contact Yakein Co., Ltd. for the latest details.