IL-36β - Human IL-36β Protein

Human IL-36β Protein (PRP1949)

产品概述

本产品为高纯度重组人源IL-36β蛋白，无标签设计，适用于细胞培养及相关科学研究。该蛋白通过大肠杆菌表达系统制备，分子量为17.37 KDa，经SDS-PAGE验证纯度超过98%。

产品特性

• 基因ID: 3082
• 蛋白质ID: Q9NZH7-2
• 氨基酸序列: Arg5-Glu164 (UniProt: Q9NZH7)
• 蛋白长度: 160个氨基酸
• 表达宿主: 大肠杆菌表达系统
• 内毒素水平: <0.1 EU/μg (LAL法测定)
• 产品形式: 冻干粉（缓冲体系：20 mM Tris, 150 mM NaCl, pH 7.4）

应用与背景

Interleukin-36 beta (IL-36β)是一种18 kDa的细胞因子，属于IL-1家族成员（IL-1F8）。它在角质形成细胞中表达，并通过结合IL-36R参与炎症反应的调控。研究表明，IL-36β在诱导T细胞分化、中性粒细胞招募以及促进IL-17C、G-CSF、IL-8、CXCL-1和TNF等细胞因子和趋化因子的表达中发挥重要作用。

使用说明

• 复溶建议: 推荐使用配套复溶缓冲液，浓度不低于100 µg/mL
• 保存条件: 冻干粉置于-20℃以下干燥环境；复溶后4℃可保存2–7天，长期保存需添加载体蛋白（0.1% HSA或BSA）并分装存于-20℃
• 注意事项: 使用前请离心，避免反复冻融

规格与价格

规格	价格（元）	货期
5 μg	588	现货（次日发货）
20 μg	1498	现货（次日发货）
100 μg	1998	现货（次日发货）
1 mg	请咨询	请咨询

运输与警告

运输条件: 蓝冰冰袋运输

使用声明: 本品仅供科研使用，不适用于人体或临床诊断。使用者应自行确保应用不侵犯专利或许可证规定。

更多信息可参考UniProt序列数据库：Q9NZH7

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Human IL-36β Protein (PRP1949)

Product Overview

This product is a high-purity recombinant human IL-36β protein with a tag-free design, suitable for cell culture and related scientific research. The protein is produced using an E. coli expression system, has a molecular weight of 17.37 kDa, and exhibits a purity greater than 98% as verified by SDS-PAGE.

Product Characteristics

• Gene ID: 3082
• Protein ID: Q9NZH7-2
• Amino Acid Sequence: Arg5-Glu164 (UniProt: Q9NZH7)
• Protein Length: 160 amino acids
• Expression Host: E. coli Expression System
• Endotoxin Level: <0.1 EU/μg (determined by LAL method)
• Product Form: Lyophilized powder (Buffer system: 20 mM Tris, 150 mM NaCl, pH 7.4)

Application and Background

Interleukin-36 beta (IL-36β) is an 18 kDa cytokine belonging to the IL-1 family (IL-1F8). It is expressed in keratinocytes and participates in the regulation of inflammatory responses by binding to IL-36R. Research indicates that IL-36β plays important roles in inducing T cell differentiation, recruiting neutrophils, and promoting the expression of cytokines and chemokines such as IL-17C, G-CSF, IL-8, CXCL-1, and TNF.

Usage Instructions

• Reconstitution Recommendation: It is recommended to use the provided reconstitution buffer at a concentration not less than 100 µg/mL.
• Storage Conditions: Lyophilized powder should be stored dry below -20°C; after reconstitution, it can be stored at 4°C for 2–7 days. For long-term storage, add a carrier protein (0.1% HSA or BSA) and aliquot store at -20°C.
• Precautions: Centrifuge before use and avoid repeated freeze-thaw cycles.

Specifications and Pricing

Specification	Price (CNY)	Lead Time
5 μg	588	In stock (ships next day)
20 μg	1498	In stock (ships next day)
100 μg	1998	In stock (ships next day)
1 mg	Please inquire	Please inquire

Shipping and Warning

Shipping Conditions: Shipped with blue ice packs.

Usage Statement: This product is intended for research use only and is not suitable for human use or clinical diagnosis. Users are responsible for ensuring that their application does not infringe upon any patents or licensing agreements.

For more information, please refer to the UniProt sequence database: Q9NZH7

Note: The above information is subject to change due to factors such as product optimization and upgrades. For specific details, please consult Yakeyin Company.