- 询价
- Nebulabio
- 中国
- NBL-289403
- 2025年12月23日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
见COA
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug; 500ug; 1mg; Bulk
| 产品信息
品名：NebuSelect™ Recombinant Human Microtubule-associated Tau
中文名称：重组人Microtubule-associated Tau蛋白
别名：P10636-8
货号：NBL-289403
品牌：Nebulabio
规格：100UG；1MG；Bulk
| 产品描述
NebuSelect™ Recombinant Human Microtubule-associated Tau (CAT#NBL-289403) is expressed in E.coli. This recombinant protein is of high purity, verified to be greater than 95% by SDS-PAGE. Endotoxin levels are less than 1 EU/µg, as determined by the LAL (Limulus Amebocyte Lysate) assay. Please contact us freely to get bioactivity data.
| 产品属性
Species:Human
Expression System:E.coli
Molecular Weight:see COA
Target Name:Microtubule-associated Tau
Purity:＞95%
Formulation:See COA
Endotoxin:＜1 EU/ug(LAL Method)
Storage:4°C for short term. -20°C for long term.
For Research Use Only!
To get more information, please contact us freely.
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文献和实验微管结合蛋白(microtubule-associated proteins, MAPs)
-X,作为同带负电的微管蛋白结合的位点。这些位点可中和微管中微管蛋白间的电荷, 维持聚合体的稳定。 Ⅱ型MAP包括MAP2、MAP4、Tau。这些蛋白有几个与微管蛋白结合的18氨基酸重复序列。 MAPs具有多方面的功能∶①使微管相互交联形成束状结构，也可以使微管同其它细胞结构交联。②通过与微管成核点的作用促进微管的聚合。③在细胞内沿微管转运囊泡和颗粒，因为一些分子马达能够同微管结合转运细胞的物质。④提高微管的稳定性∶由于MAPs同微管壁的结合，自然就改变了微管组装和解
of microtubule-associated proteins. Tau is strongly expressed in neurons, localized in the axon and is essential for neuronal architecture, plasticity and network. In animal models, overexpression of mutated Tau proteins is often used to induce a Tau pathology
Tau Phosphorylation Both In Vitro and in Cells
Tau was originally isolated from brain microtubules and shown to be a microtubule-associated protein (MAP) that promoted tubulin polymerization (1 ). It is largely confined to axons, where it is the major MAP. It promotes microtubule nucleation
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