- ￥780 - 17280
- 普诺赛
- PCK027
- 武汉
- 2025年12月23日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
99
- 供应商：
武汉普诺赛生命科技有限公司
- 英文名：
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant
- 规格：
10μg/50μg/500μg/1mg
| 规格： | 10μg | 产品价格： | ￥780.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥1880.0 |
| 规格： | 500μg | 产品价格： | ￥11880.0 |
| 规格： | 1mg | 产品价格： | ￥17280.0 |
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant,HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant
Hepatocyte Growth Factor Receptor (HGF R) is a glycosylated Receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domain, consist of secreted extracellular domains, or are deficient in proteolytic separation of the α and β chains. The sema domain, which is formed by both α and β chains of HGF R, mediates both Ligand binding and Receptor dimerization. HGF stimulation induces HGF R downregulation via internalization and proteasomedependent degradation. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGF R on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
产品优势：
1、专为细胞培养和研究而设计；
2、低内毒素水平≤0.1 EU/μg，高纯度≥95%；
3、高生物学活性，经严格的质控和细胞功能学测试和验证；
4、产品类型丰富，多个种属因子可供选择。
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant建议储存于Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
Hepatocyte Growth Factor Receptor (HGF R) is a glycosylated Receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domain, consist of secreted extracellular domains, or are deficient in proteolytic separation of the α and β chains. The sema domain, which is formed by both α and β chains of HGF R, mediates both Ligand binding and Receptor dimerization. HGF stimulation induces HGF R downregulation via internalization and proteasomedependent degradation. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGF R on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
产品优势：
1、专为细胞培养和研究而设计；
2、低内毒素水平≤0.1 EU/μg，高纯度≥95%；
3、高生物学活性，经严格的质控和细胞功能学测试和验证；
4、产品类型丰富，多个种属因子可供选择。
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant建议储存于Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
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文献和实验该产品被引用文献
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant
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文献支持
HGF R/c-Met/HGFR (Glu25-Gly519), Human, Recombinant
￥780 - 17280
