- 询价
- abinScience
- China
- HW821035
- 2026年03月03日
- ELISA, IHC, WB
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
E. coli - derived recombinant human PSEN2 (Lys271-Lys361).
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
0.01M PBS, pH 7.4.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
1 year
- 抗原来源：
Mouse
- 目录编号：
HW821035
- 级别：
科研级别
- 库存：
999
- 供应商：
abinScience
- 宿主：
Mouse
- 应用范围：
ELISA, IHC, WB
- 浓度：
1mg/ml
- 靶点：
Presenilin-2, PS-2, EC:3.4.23.-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2
- 抗体英文名：
Anti-Human PSEN2 Monoclonal Antibody (1A531)
- 抗体名：
Anti-Human PSEN2 Monoclonal Antibody (1A531)
- 规格：
50ug/100ug
| Product name | Anti-Human PSEN2 Monoclonal Antibody (1A531) |
|---|---|
| Catalog No. | HW821035 |
| Host species | Mouse |
| Species reactivity | Human |
| Immunogen | E. coli - derived recombinant human PSEN2 (Lys271-Lys361). |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Clonality | Monoclonal |
| Isotype | IgG |
| Applications | ELISA, IHC, WB |
| Target | Presenilin-2, PS-2, EC:3.4.23.-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | \ |
| Accession | P49810 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Clone ID | 1A531 |
| Note | For research use only. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for ab...
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Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
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Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验• Alzheimer's disease risk genes and mechanisms of disease pathogenesis. PMID: 24951455
• Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. PMID: 12691659
• Alzheimer's Disease Associated Presenilin 1 and 2 Genes Dysregulation in Neonatal Lymphocytes Following Perinatal Asphyxia. PMID: 34067945
• Alzheimer's disease: genes, proteins, and therapy. PMID: 11274343
• Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development. PMID: 37864790
• PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca2+ homeostasis. PMID: 30892128
• Familial Alzheimer's disease sustained by presenilin 2 mutations: systematic review of literature and genotype-phenotype correlation. PMID: 24594196
• Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk. PMID: 21285369
• Presenilin-interacting proteins. PMID: 14585160
of a mouse-human chimeric monoclonal antibody to Cd20 with potent Fc-dependent biologic activity. J.Immunol.，1987，139：3521[4]Press ow，Farr AG，Borroz KI，et al. Endocytosis and degradation of monoclonal antibodies targeting human B-celll malignancies. Cancer
；7：711[6] 杨希峰，沈德诚，金宇光等. HI47，一种人成熟B细胞单克隆抗体制备，鉴定及其生物特性研究。上海免疫学杂志，1990；10（2）：65-68[7] McLaughlin P，Grillo-Lopez AJ， Link BK，et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma：half of patient respond to a four-dose
Aldrich) ( 保存于 2~8℃）。 2 ) 特异抗体免疫检测方法 ( 1 ) TBS 缓冲液：20 mmol/L Tris -HCl，pH 7.4，含 0. 5 mol/L NaCl。 ( 2 ) 明胶（Bio- Rad) 。 ( 3 ) 抗 HRP 免疫兔血清 （Sigma Aldrich ) ( 保存于 2~8°C ) 。 ( 4 ) 抗蜂毒抗体（蜂毒， Sigma Aldrich ) ( 保存于 2~8°C ) 。 ( 5 ) 鼠抗人
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