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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 保质期:
6个月
- 英文名:
Recombinant Mouse Apoptosis-associated speck-like protein containing a CARD (Pycard), partial
- 库存:
详询客服
- 供应商:
biorbyt
- 规格:
20 ug
产品别名:(mASC)(PYD and CARD domain-containing protein)
应用笔记:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
纯度:Greater than 90% as determined by SDS-PAGE.
生物来源:Mus musculus (Mouse)
蛋白序列:MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQMDAIDLTDKLVSYYLESYGLELTMTVLRDMGLQELAEQLQTTKEESGAVAAAASVPAQSTARTGHFVDQHRQALIARVTEVDGVLDALHGSVLTEGQYQAVRAETTSQDKMRKLFSFVPSWNLTCKDSLLQALKEIHPYLVMDLEQS
分子量:21.5 kDa
表达区域:1-193aa
标签:Tag-Free
防腐剂:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
来源:E.coli
形态:Liquid or Lyophilized powder
Uniprot ID:Q9EPB4
Note:For research use only.

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文献和实验ASC Speck Formation as a Readout for Inflammasome Activation
All inflammasomes require the adapter protein apoptosis associated speck-like protein containing a CARD (ASC) for the activation of caspase-1. After inflammasome activation, ASC assembles into a large protein complex, which is termed “speck
炎症促发阿尔茨海默病又添一力证!NLRP3 炎症小体激活引发 tau 蛋白异常
regeneration,ALR)蛋白家族作为受体蛋白(receptor)、凋亡相关微粒蛋白(apoptosis-associated speck-like protein containing CARD)ASC 作为接头蛋白(adaptor)、含半胱氨酸的天冬氨酸蛋白水解酶 caspase 作为效应蛋白(effector)。其中接头蛋白 ASC 包含两个重要的结构域即 PYD 和 CARD。CARD 结构域发挥桥梁作用,连接受体蛋白和效应蛋白,ASC 的 CARD 结构域可与效应蛋白 CARD 结构域结合形成
【共享】某机构发表的核酸相关研究的文章(EST,SNP等),PDF全文下载
, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S (2006) A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways Proc
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