- 询价
- BIO-RAD
- MCA4646SBUV540
- 2025年12月11日
- F
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD335-Fc fusion protein
- 亚型：
IgG1
- 形态：
Purified IgG conjugated to StarBright UltraViolet 540 - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
StarBright UltraViolet 540
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
9E2
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
F
- 浓度：
For information on the concentration of our StarBright Dye conjugated reagents please visit our FAQ page.
- 抗体名：
CD335 antibody | 9E2
- 规格：
100 Tests/0.5ml
Mouse anti Human CD335 antibody, clone 9E2 recognizes human NK (natural killer) cell-specific marker CD335, otherwise known as NKp46, a 46kDa type I transmembrane glycoprotein, and the first identified member of the natural cytotoxicity receptor (NCR) family.
CD335 is uniquely expressed by all resting and activated NK cells, and considered to be the major NK cell lysis receptor for autologous pathogen-infected and tumour target cells, during natural cytotoxicity responses. Ligands of CD335 include viral haemagglutinins (HAs), and heparan sulphate proteoglycans (HSPGs) on the surface of tumour cells.
Mouse anti Human CD335 antibody, clone 9E2 mediates re-directed NK cell cytotoxicity (Yusa et al. 2002, Chen et al. 2007).
CD335 is uniquely expressed by all resting and activated NK cells, and considered to be the major NK cell lysis receptor for autologous pathogen-infected and tumour target cells, during natural cytotoxicity responses. Ligands of CD335 include viral haemagglutinins (HAs), and heparan sulphate proteoglycans (HSPGs) on the surface of tumour cells.
Mouse anti Human CD335 antibody, clone 9E2 mediates re-directed NK cell cytotoxicity (Yusa et al. 2002, Chen et al. 2007).
储存信息
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted.
This product should be stored undiluted.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | Neat |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 5μl of the suggested working dilution to label 106 cells in 100μl. Best practices suggest a 5 minutes centrifugation at 6,000g prior to sample application.
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文献和实验该产品被引用文献
References for CD335 antibody
- Yusa, S. et al. (2002) SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells.
J Immunol. 168 (10): 5047-57. - Chklovskaia, E. et al. (2004) Reconstitution of dendritic and natural killer-cell subsets after allogeneic stem cell transplantation: effects of endogenous flt3 ligand.
Blood. 103 (10): 3860-8. - Chen, Y. et al. (2007) Prostaglandin D2 suppresses human NK cell function via signaling through D prostanoid receptor.
J Immunol. 179 (5): 2766-73.
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Mouse anti Human CD335:StarBright UltraViolet 540
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