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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1
- 形态:
Purified IgG conjugated to StarBright UltraViolet 740 - liquid
- 克隆性:
Monoclonal Antibody
- 标记物:
StarBright UltraViolet 740
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
LT19
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
F
- 浓度:
For information on the concentration of our StarBright Dye conjugated reagents please visit our FAQ page.
- 抗体名:
CD19 antibody | LT19
- 规格:
100 Tests/0.5ml
Mouse anti Human CD19 antibody, clone LT19 recognizes human CD19 also known as T-cell surface antigen Leu-12 or B-lymphocyte surface antigen B4. CD19 is a ~95 kDa type I single pass transmembrane glycoprotein expressed on follicular dendritic cells and B-cells during maturation but is lost on development into plasma cells (de Rie et al. 1989).
CD19 is the broadest lineage specific marker for B cells and functions as a B-cell co-receptor in conjunction with CD21 (Bradbury et al. 1992), CD9, CD81 and CD82 (Horváth et al. 1998). CD19 is implicated in the down-regulation of B cell growth and proliferation (Pezzutto et al. 1987).
CD19 is the broadest lineage specific marker for B cells and functions as a B-cell co-receptor in conjunction with CD21 (Bradbury et al. 1992), CD9, CD81 and CD82 (Horváth et al. 1998). CD19 is implicated in the down-regulation of B cell growth and proliferation (Pezzutto et al. 1987).
储存信息
This product is shipped at ambient temperature.
Store at +4°C.
DO NOT FREEZE.
This product should be stored undiluted.
Store at +4°C.
DO NOT FREEZE.
This product should be stored undiluted.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | Neat |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 5μl of the suggested working dilution to label 106 cells in 100μl. Best practices suggest a 5 minutes centrifugation at 6,000g prior to sample application.
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文献和实验该产品被引用文献
References for CD19 antibody
- Hughes, G.J. et al. (2007) Virus immunocapture provides evidence of CD8 lymphocyte-derived HIV-1 in vivo.
AIDS. 21: 1507-13. - Allen, J.S. et al. (2009) Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture.
Diabetes. 58: 138-45. - McIntosh, K. et al. (2006) The immunogenicity of human adipose-derived cells: temporal changes in vitro.
Stem Cells. 24: 1246-53. - Sengstake, S. et al. (2006) CD21 and CD62L shedding are both inducible via P2X7Rs.
Int Immunol. 18 (7): 1171-8. - Villarroel Dorrego, M. et al. (2006) Transfection of CD40 in a human oral squamous cell carcinoma keratinocyte line upregulates immune potency and costimulatory molecules.
Br J Dermatol. 154: 231-8. - Franz, B. et al. (2011) Ex vivo characterization and isolation of rare memory B cells with antigen tetramers.
Blood. 118: 348-57. - Lacal, P.M. et al. (2013) Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion.
J Pharmacol Exp Ther. 347: 164-72. - Franz, B. et al. (2011) Ex vivo characterization and isolation of rare memory B cells with antigen tetramers.
Blood. 118: 348-57.
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Mouse anti Human CD19:StarBright UltraViolet 740
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