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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Villin
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL815
- 标记物:
Vio B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
Villin Antibody, anti-human, REAdye_lease™
- 抗体名:
Villin Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of Villin+ cellsClone REAL815 is an antibody fragment derived from the full Villin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL815 recognizes human Villin protein, also known as Villin-1, a member of a family of calcium-regulated actin-binding proteins encoded by the VIL1 gene. This protein represents a dominant part of the brush border cytoskeleton and plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Villin regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis and enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Wang, Y. et al. (2008) A novel role for villin in intestinal epithelial cell survival and homeostasis. J. Biol. Chem. 283 (14): 9454–9464. | Srivatsa, S. et al. (2017) EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patient. Gastroenterology 153 (1): 178–190. | Izdebska, M. et al. (2020) Involvement of Actin and Actin-Binding Proteins in Carcinogenesis. Cells 9 (10): 2245.
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Villin Antibody, anti-human, Vio® B515, REAdye_lease™, 200 µL
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