- 询价
- Miltenyi Biotec
- 德国
- 130-132-849
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Podoplanin
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL1387
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
Podoplanin Antibody, anti-mouse, REAdye_lease™
- 抗体名：
Podoplanin Antibody, anti-mouse, REAdye_lease™
- 规格：
200 µL
Detection of Podoplanin+ cellsClone REAL1387 is an antibody fragment derived from the full mouse Podoplanin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1387 recognizes Podoplanin, a mucin-type glycoprotein thought to be involved in the development of the lymphatic vascular system. Podoplanin mediates effects on cell migration and adhesion through its different partners and has a potential role in tumor progression. During development it plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Bieniasz-Krzywiec, P. et al. (2019) Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer. Cell Metab. 30 (5): 917–936. | Suzuki-Inoue, K. (2019) Platelets and cancer-associated thrombosis: focusing on the platelet activation receptor CLEC-2 and podoplanin. Blood 134 (22): 1912–1918. | Ukaji, T. et al. (2021) Novel knock-in mouse model for the evaluation of the therapeutic efficacy and toxicity of human podoplanin-targeting agents. Cancer Sci. 112 (6): 2299–2313.
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Podoplanin Antibody, anti-mouse, PE, REAdye_lease™, 200 µL
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