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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Podocalyxin
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1394
- 标记物:
Vio B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
Podocalyxin Antibody, anti-human, REAdye_lease™
- 抗体名:
Podocalyxin Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of Podocalyxin+ cellsClone REAL1394 is an antibody fragment derived from the full Podocalyxin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1394 recognizes Podocalyxin, also known as PCLP1 and PODXL, a single-pass type I membrane sialoglycoprotein. Podocalyxin is involved in the regulation of adhesion, cell morphology and cancer progression. It is most closely related to CD34 and endoglycan, expressed by kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons. Podocalyxin plays a role in cancer development and aggressiveness by inducing cell migration and invasion. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and tumour marker. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Nielsen, J. S. et al. (2009) The role of podocalyxin in health and disease. J. Am. Soc. Nephrol. 20 (8): 1669–1676. | Toyoda, H. et al. (2017) Podocalyxin as a major pluripotent marker and novel keratan sulfate proteoglycan in human embryonic and induced pluripotent stem cells. Glycoconj J 34 (2): 139–145. | Le Tran, W. et al. (2021) Podocalyxin in Normal Tissue and Epithelial Cancer. Cancers (Basel) 13 (12): 3863.
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Podocalyxin Antibody, anti-human, Vio® B515, REAdye_lease™, 200 µL
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