- 询价
- Miltenyi Biotec
- 德国
- 130-136-394
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IDH1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL1159
- 标记物：
Vio B515
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
IDH1 Antibody, anti-human, REAdye_lease™
- 抗体名：
IDH1 Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of IDH1+ cellsClone REAL1159 is an antibody fragment derived from the full IDH1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1159 recognizes the IDH1 enzyme, also known as Isocitrate dehydrogenase (NADP) cytoplasmic, that plays an important role in lipid biosynthesis in different tissues such as the liver, adipose tissues, brain and tumors. Mutations of IDH is related to the progress and prognosis of certain tumors and have been found in numerous cancers, mainly in gliomas, chondrosarcomas or enchondromas, and cholangiocarcinomas. IDH1 is considered to be a specific biomarker for early diagnosis, prognosis and targeted therapy for tumors. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
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文献和实验该产品被引用文献
Dang, L. et al. (2009) Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 739 (744): 462–7274. | Mondesir, J. et al. (2016) IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives. J Blood Med. 7: 171–180. | Mehrjardi, M. Z. et al. (2020) Current biomarker-associated procedures of cancer modeling-a reference in the context of IDH1 mutant glioma. Cell Death Dis 11 (11): 998.
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IDH1 Antibody, anti-human, Vio® R667, REAdye_lease™, 200 µL
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