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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
GP2
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1315
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
GP2 Antibody, anti-human, REAdye_lease™
- 抗体名:
GP2 Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of GP2+ cellsClone REAL1315 is an antibody fragment derived from the full GP2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1315 recognizes the GP2 transmembranprotein, associated with the zymogen granule membranes, also known as Glycoprotein 2 and ZAP75. GP2 functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. Glycoprotein 2 is expressed on pancreatic zymogen granule membrane and also on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Clive, K. S. et al. (2012) The GP2 peptide: a HER2/neu-based breast cancer vaccine. J Surg Oncol 105 (5): 452–458. | Somma, V. et al. (2013) The Novel Crohn's Disease Marker Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease.: 683824. | Lin, Y. et al. (2020) Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Nat Commun 11 (1): 3175.
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GP2 Antibody, anti-human, APC, REAdye_lease™, 200 µL
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