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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ERp57 (PDIA3)
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1454
- 标记物:
Vio B515
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
ERp57 (PDIA3) Antibody, anti-human, REAdye_lease™
- 抗体名:
ERp57 (PDIA3) Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of ERp57 (PDIA3)+ cellsClone REAL1454 is an antibody fragment derived from the full ERp57 (PDIA3) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1454 recognizes ERp57 (PDIA3), a member of the protein disulfide family of endoplasmic reticulum localized oxidoreductases. It plays an important role in disulfide bond formation and protein folding. Along with calnexin and calreticulin, it is essential for the synthesis and quality control of nascent glycoproteins in the secretory pathway. ERp57 (PDIA3) is upregulated in multiple neurodegenerative diseases and cancers. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Lam, S. T. T. and Lim, C. J. (2021) Cancer Biology of the Endoplasmic Reticulum Lectin Chaperones Calreticulin, Calnexin and PDIA3/ERp57. Prog Mol Subcell Biol 59: 181–196. | Tanikawa, Y. et al. (2021) Ca2+ Regulates ERp57-Calnexin Complex Formation. Molecules 26 (10): 2853 doi. | Chichiarelli, S. et al. (2022) ERp57/PDIA3: new insight. Cell Mol Biol Lett 27 (1): 12.
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ERp57 (PDIA3) Antibody, anti-human, Vio® B515, REAdye_lease™, 200 µL
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