- 询价
- Miltenyi Biotec
- 德国
- 130-123-091
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Cytokeratin LMW
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL648
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
Cytokeratin LMW Antibody, anti-human, REAdye_lease™
- 抗体名：
Cytokeratin LMW Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of Cytokeratin LMW+ cellsClone REAL648 is an antibody fragment derived from the full Cytokeratin LMW antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL648 recognizes Cytokeratin LMW. Cytokeratins are polypeptides with keratin-containing intermediate filaments, which ensure form stability and cohesiveness. Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. Cytokeratin LMW detects the cytokeratins 7, 8, 18, amd 19 which are expressed in normal and abnormal human tissues in epithelial cells and carcinomas. Cytokeratin LMW is used to differentiate between epithelial carcinoma and non-epithelial malignancies. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Makin, C. A. et al. (1984) Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol 37: 975–983. | Eichner, R. et al. (1984) Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J. Cell Biol. 98 (4): 1388–1396. | Balasubramanian, P. et al. (2012) Multiparameter analysis, including EMT markers, on negatively enriched blood samples from patients with squamous cell carcinoma of the head and neck. PLoS One 7 (7): . | Xin, H. et al. (2014) Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts. PLoS One 9 (1): e85308. | Gown, A. M. et al. (1985) Monoclonal antibodies to human intermediate filament proteins. III. Analysis of tumors. Am. J. Clin. Pathol. 84 (4): 413–424. | Battifora, H. (1988) Clinical applications of the immunohistochemistry of filamentous proteins. Am J Surg Pathol 12: 24–42.
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Cytokeratin LMW Antibody, anti-human, APC, REAdye_lease™, 200 µL
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