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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Cytokeratin 18
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REAL1149
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名:
Cytokeratin 18 Antibody, anti-human, REAdye_lease™
- 抗体名:
Cytokeratin 18 Antibody, anti-human, REAdye_lease™
- 规格:
200 µL
Detection of Cytokeratin 18+ cellsClone REAL1149 is an antibody fragment derived from the full Cytokeratin 18 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1149 specifically recognizes cytokeratin 18 (K18). Cytokeratins are located in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 18 is frequently used in conjunction with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells and to enumerate circulating tumor cells in blood. Gene mutations of Keratin 18 lead in cryptogenic cirrhosis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
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文献和实验该产品被引用文献
Oshima, R. G. et al. (1986) Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation. Differentiation 33 (1): 61–68. | Waseem, A. et al. (1990) Embryonic simple epithelial keratins 8 and 18: chromosomal location emphasizes difference from other keratin pairs. New Biol. 2 (5): 464–478. | Ku, N. O. et al. (2003) Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies. Proc. Natl. Acad. Sci. U.S.A. 100 (10): 6063–6068.
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Cytokeratin 18 Antibody, anti-human, PE, REAdye_lease™, 200 µL
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