- 询价
- Miltenyi Biotec
- 德国
- 130-128-916
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
MYH7B
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL1165
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
MYH7B Antibody, anti-human, REAdye_lease™
- 抗体名：
MYH7B Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of MYH7B+ cellsClone REAL1165 is an antibody fragment derived from the full MYH7B antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1165 recognizes human protein MYH7B, also known as myosin, heavy chain 7B or Myosin-7B, which is a member of the motor-domain superfamily. MYH7B is expressed in extraocular muscles and muscle spindles in heart, skeletal muscle and testis, but also in liver, spleen, lung and pancreas. MYH7B plays a role in muscle contraction. MYH7B is supposed to cause heart diseases including Hypertrophic cardiomyopathy (HCM), Left Ventricular Noncompaction (LVHT) and Dilated Cardiomyopathy. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
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文献和实验该产品被引用文献
Peter, A. K. et al. (2019) Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy. J Am Heart Assoc. 8 (15): . | Rossi, A. C. et al. (2010) Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles. J Physiol 588: 353–364. | Desjardins, P. R. et al. (2002) Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family. Mol. Biol. Evol. 19 (4): 375–393. | Chen, P. et al. (2020) MYH7B variants cause hypertrophic cardiomyopathy by activating the CaMK-signaling pathway. Sci. China Life Sci. 63 (9): 1347–1362.
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MYH7B Antibody, anti-human, FITC, REAdye_lease™, 200 µL
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