- 询价
- Miltenyi Biotec
- 德国
- 130-126-437
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Metallothionein
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL639
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
Metallothionein Antibody, anti-human, REAdye_lease™
- 抗体名：
Metallothionein Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of Metallothionein+ cellsClone REAL639 is an antibody fragment derived from the full Anti-Metallothionein antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL639 recognizes the human Metallothionein, a cytoplasmatic protein, which has a high content of cysteine and no aromatic amino acids. Metallothionein is able to bind and sequestrate heavy metal ions and is transcriptionally regulated by heavy metals, glucocorticoids, interferon, lymphokines and stress. The isoforms of Metallothionein MT I and MT II have the ability to scavenge free radicals and play a role in carcinogenesis. Overexpression is found in cancers, e.g. different carcinomas and melanoma. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
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文献和实验该产品被引用文献
Kägi, J .H. et al. (1974) Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content. J. Biol. Chem. 249 (11): 3537–3542. | Kumari, M. V. et al. (1998) Free radical scavenging actions of metallothionein isoforms I and II. Free Radic. Res. 29 (2): 93–101. | Tuccari, G. et al. (2000) Immunohistochemical detection of metallothionein in carcinomatous and normal human gastric mucosa. Histol. Histopathol. 15 (4): 1035–1041.
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文献支持
Metallothionein Antibody, anti-human, PE, REAdye_lease™, 200 µL
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