CD326 (EpCAM) Antibody, anti-human, PE, REAdye_lease™, 200 µL
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CD326 (EpCAM) Antibody, anti-h

uman, PE, REAdye_lease™, 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-133-242
  • 2025年12月09日
  • MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • cell line
  • human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD326 (EpCAM)

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REAL1555

    • 标记物

      PE

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      cell line

    • 应用范围

      MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 抗体英文名

      CD326 (EpCAM) Antibody, anti-human, REAdye_lease™

    • 抗体名

      CD326 (EpCAM) Antibody, anti-human, REAdye_lease™

    • 规格

      200 µL

    Detection of CD326 (EpCAM)+ cellsClone REAL1555 is an antibody fragment derived from the full CD326 (EpCAM) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1555 recognizes the pleiotropic molecule CD326 (EpCAM), which is also known as epithelial cell adhesion molecule (EpCAM). It is involved in cell adhesion, mediates intercellular adhesion and associates with the actin cytoskeleton. The CD326 antigen is an useful diagnostic marker for epithelia and epithelial-derived neoplasm. It is found in metastases, malignant effusions, and cancer stem cells. It is overexpressed in certain carcinomas including colon, pancreas, breast and most adenocarcinomas. CD326 (EpCAM) is not detected on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. Furthermore, it is suggested, that CD326 could be used as a surface marker for human ESCs. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |

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    图标文献和实验
    该产品被引用文献
    Moldenhauer, G. et al. (1987) Epithelium specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. Br. J. Cancer 56: 714–721. | Sheridan, C. et al. (2006) CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res. 8 (5): R59. | Sundberg, M. et al. (2009) CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells. Stem Cell Res. 2 (2): 113–124. | Metsuyanim, S. et al. (2009) Expression of stem cell markers in the human fetal kidney. PLoS One 4 (68): e6709. | Matsumoto, T. et al. (2017) Proliferating EpCAM-Positive Ductal Cells in the Inflamed Liver Give Rise to Hepatocellular Carcinoma. Cancer Res. 77 (22): 6132–6143. | Ouchi T et al. (2021) EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase. Cells 10 (2): 256.
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    文献支持
    CD326 (EpCAM) Antibody, anti-human, PE, REAdye_lease™, 200 µL
    询价