- 询价
- Miltenyi Biotec
- 德国
- 130-131-852
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Carboxypeptidase A1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL1385
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
Carboxypeptidase A1 Antibody, anti-human, REAdye_lease™
- 抗体名：
Carboxypeptidase A1 Antibody, anti-human, REAdye_lease™
- 规格：
200 µL
Detection of Carboxypeptidase A1+ cellsClone REAL1385 is an antibody fragment derived from the full Carboxypeptidase A1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1385 recognizes the zinc metalloprotease Carboxypeptidase A1, encoded by the CPA1 gene and belongs to the peptidase M14 family. It is a monomeric pancreatic exopeptidase, that catalyzes the release of a C-terminal amino acid, the conversion of leukotriene C4 to leukotriene F4 and is involved in zymogen inhibition. CPA1 is associated with pancreatic cancer susceptibility and implicate ER stress in pancreatic acinar cells in pancreatic cancer development. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Tamura K. et al. (2018) Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc. Natl. Acad. Sci. U.S.A. 115 (18): 4767–4772. | Said, S. et al. (2020) Carboxypeptidase A1 and regenerating islet-derived 1α as new markers for pancreatic acinar cell carcinoma. Hum. Pathol. 103: 120–126. | Uhlig, R. et al. (2022) Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas. Am J Surg Pathol 46 (1): 97–104.
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Carboxypeptidase A1 Antibody, anti-human, PE, REAdye_lease™, 200 µL
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