- 询价
- Miltenyi Biotec
- 德国
- 130-129-898
- 2025年12月09日
- MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD49f
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL242
- 标记物：
PE
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 抗体英文名：
CD49f Antibody, anti-mouse, REAdye_lease™
- 抗体名：
CD49f Antibody, anti-mouse, REAdye_lease™
- 规格：
200 µL
Detection of CD49f+ cellsClone REAL242 is an antibody fragment derived from the full CD49f antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL242 recognizes the CD49f antigen, a 120kD Single-pass type I membrane protein which is also known as Integrin alpha-6 (ITGA6). Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
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文献和实验该产品被引用文献
Hemler, M. E. et al. (1988) Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures. J. Biol. Chem. 263: 7660–7665. | Carter, W. G. et al. (1990) Distinct functions for integrins α 3 β 1 in focal adhesions and α 6 β 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes. J. Cell Biol. 111: 3141–3154. | Aumailley, M. et al. (1990) Antibody to integrin α 6 subunit specifically inhibits cell-binding to laminin fragment 8. Exp. Cell Res. 188 (1): 55–60. | Hynes, R. O. (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110 (6): 673–687. | Izadyarz, F. et al. (2011) Identification and characterization of repopulating spermatogonial stem cells from the adult human testis. Hum. Reprod. 26 (6): 1296–1306.
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CD49f Antibody, anti-mouse, PE, REAdye_lease™, 200 µL
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