- 询价
- Miltenyi Biotec
- 德国
- 130-122-633
- 2025年12月09日
- Flow cytometry
- cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD127
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REAL102
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD127 Antibody, anti-human, REAlease®
- 抗体名：
CD127 Antibody, anti-human, REAlease®
- 规格：
100 tests
Identification and enumeration of CD127+ cells by flow cytometryClone REAL102 is an antibody fragment derived from the full CD127 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL102 recognizes the CD127 antigen, which is the α-chain of the interleukin 7 (IL-7) receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc). CD127 can be identified on immature B cells through the early pre–B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation. On regulatory T cells CD127 is absent and its expression is inversely correlated with FoxP3 expression and suppressive function. CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
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文献和实验该产品被引用文献
Armitage, R. J. et al. (1991) Expression of receptors for interleukin 4 and interleukin 7 on human T cells. Adv. Exp. Med. Biol. 292: 121–130. | Sudo, T. et al. (1993) Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 90: 9125–9129. | Fry, T. J. and Mackall, C. L. (2002) Interleukin-7: from bench to clinic. Blood 99: 3892–3904. | Cupedo, T. et al. (2005) Development and activation of regulatory T cells in the human fetus. Eur. J. Immunol. 35: 383–390. | Liu, S. et al. (2006) Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 66 (12): 6063–6071. | Seddiki, N. et al. (2006) Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203: 1693–1700.
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CD127 Antibody Kit, anti-human, FITC, REAlease®, 100 tests
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