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CD87 Antibody, anti-human, Vio

® Bright V423, REAfinity™, 100 tests in 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-128-534
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD87

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA892

    • 标记物

      Vio Bright V423

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      CD87 Antibody, anti-human, REAfinity™

    • 抗体名

      CD87 Antibody, anti-human, REAfinity™

    • 规格

      100 tests in 200 µL

    Identification and enumeration of CD87+ cells by flow cytometryClone REA892 recognizes the human CD87 antigen, a 36–38 kDa GPI-anchored cell-surface receptor. CD87, also known as uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling. | Additional information: Clone REA892 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    May, A. E. et al. (1998) Urokinase receptor (CD87) regulates leukocyte recruitment via β2 integrins in vivo. J. Exp. Med. 188: 1029–1037. | Tarui, T. et al. (2001) Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J. Biol. Chem. 276: 3983–3990. | Ge, Y. et al. (2003) Urokinase plasminogen activator receptor (CD87): something old, something new. Lab. Hematol. 9 (2): 67–71.
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    CD87 Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
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