- 询价
- Miltenyi Biotec
- 德国
- 130-114-849
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD87
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA892
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD87 Antibody, anti-human, REAfinity™
- 抗体名：
CD87 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of CD87+ cells by flow cytometryClone REA892 recognizes the human CD87 antigen, a 36–38 kDa GPI-anchored cell-surface receptor. CD87, also known as uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling. | Additional information: Clone REA892 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
May, A. E. et al. (1998) Urokinase receptor (CD87) regulates leukocyte recruitment via β2 integrins in vivo. J. Exp. Med. 188: 1029–1037. | Tarui, T. et al. (2001) Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J. Biol. Chem. 276: 3983–3990. | Ge, Y. et al. (2003) Urokinase plasminogen activator receptor (CD87): something old, something new. Lab. Hematol. 9 (2): 67–71.
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CD87 Antibody, anti-human, FITC, REAfinity™, 100 tests in 200 µL
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