- 询价
- Miltenyi Biotec
- 德国
- 130-109-854
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD87
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA630
- 标记物：
Biotin
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
CD87 Antibody, anti-mouse, REAfinity™
- 抗体名：
CD87 Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of CD87+ cells by flow cytometryClone REA630 recognizes the mouse CD87 antigen, a key molecule involved in invasive migration of angiogenic endothelium, also known as uPAR. CD87 binds uPA (urokinase plasminogen activator) and thus facilitates the catalytic C domain of the uPA to come in close proximity of membranebound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. CD87 is expressed in angiogenic endothelial cells. | Additional information: Clone REA630 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Miljkovic-Licina, M. et al. (2009) Sushi repeat protein X-linked 2, a novel mediator of angiogenesis. FASEB J. 23 (12): 4105–4116. | Lin, L. et al. (2010) Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy. J. Biol. Chem. 285 (14): 10982–10992. | Suh, T. T. et al. (1994) The murine urokinase-type plasminogen activator receptor gene. J. Biol. Chem. 269 (42): 25992–25998.
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CD87 Antibody, anti-mouse, Biotin, REAfinity™, 30 µg in 1 mL
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