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CD86 Antibody, anti-human, Vio

® Bright V600, REAfinity™, 30 tests in 60 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-132-295
  • 2025年12月09日
  • Flow cytometry, Mass cytometry
  • human cell line
  • human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD86

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA968

    • 标记物

      Vio Bright V600

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry, Mass cytometry

    • 浓度

      1:50

    • 抗体英文名

      CD86 Antibody, anti-human, REAfinity™

    • 抗体名

      CD86 Antibody, anti-human, REAfinity™

    • 规格

      30 tests in 60 µL

    Identification and enumeration of CD86+ cells by flow cytometryClone REA968 recognizes the human CD86 antigen, also known as B7-2 or B70, which is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of co-stimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells, and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell costimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of costimulatory signals for activation or proliferation of T cells or cytokine production. | Additional information: Clone REA968 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Azuma, M. et al. (1993) B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366 (6450): 76–79. | Engel, P. et al. (1994) The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood 84 (5): 1402–1407. | Lanier, L. L. et al. (1995) CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 154 (1): 97–105.
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    文献支持
    CD86 Antibody, anti-human, Vio® Bright V600, REAfinity™, 30 tests in 60 µL
    询价