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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD8b
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA222
- 标记物:
PE
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:10
- 抗体英文名:
CD8b Antibody, anti-rat, REAfinity™
- 抗体名:
CD8b Antibody, anti-rat, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of CD8b+ cells by flow cytometryClone REA222 recognizes rat CD8b, a member of the immunoglobulin superfamily also known as T cell surface glycoprotein Lyt-3. CD8b is expressed on cytotoxic T cells, thymocytes, and macrophages as a heterodimer with CD8a. CD8 identifies cytotoxic/suppressor T cells that interact with MHC class I bearing targets and plays a role in the process of T cell mediated killing. Flow cytometric analysis showed that CD8 T cells from lymph nodes or spleen of normal rats almost exclusively express the α/β heterodimer, regardless of the T cell receptor isotype. In contrast, natural killer cells carry only CD8a chains. | Additional information: Clone REA222 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Torres-Nagel, N. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22 (11): 2841–2848. | Duplan, V. et al. (2007) Tracking antigen-specific CD8+ T cells in the rat using MHC class I multimers. J. Immunol. Methods 320 (1-2): 30–39.
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CD8b Antibody, anti-rat, PE, REAfinity™, 9 µg in 300 µL
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