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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD8a
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA601
- 标记物:
PerCP
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
CD8a Antibody, anti-mouse, REAfinity™
- 抗体名:
CD8a Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of CD8a+ cells by flow cytometryClone REA601 is specific for the mouse CD8a antigen, also known as LY-2 or T8, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ+ cells. CD8a is further detected on most thymocytes (CD4+CD8a+ and CD4–CD8+ thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ+ cells express a CD8a/CD8a homodimer. It mediates efficient cell-cell interactions within the immune system. | Additional information: Clone REA601 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Liaw, C. W. et al. (1986) Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene. J Immunol 137 (3): 1037–1043. | Nakauchi, H. et al. (1985) Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proc. Natl. Acad. Sci. U.S.A. 82 (15): 5126–5130. | Nakauchi, H. et al. (1987) Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nucleic Acids Res. 15 (10): 4337–4347.
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CD8a Antibody, anti-mouse, PerCP, REAfinity™, 30 µg in 200 µL
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