- 询价
- Miltenyi Biotec
- 德国
- 130-108-907
- 2025年12月09日
- Flow cytometry
- human cell line
- rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD8a
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA437
- 标记物：
Biotin
- 适应物种：
rat
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:10
- 抗体英文名：
CD8a Antibody, anti-rat, REAfinity™
- 抗体名：
CD8a Antibody, anti-rat, REAfinity™
- 规格：
9 µg in 300 µL
Identification and enumeration of CD8a+ cells by flow cytometryClone REA437 recognizes the rat CD8a antigen, a single-pass type I membrane protein, which is also known as OX-8. CD8 acts as a co-receptor for the T cell receptor and recognizes antigen displayed by an antigen presenting cell in the context of class I MHC molecules. CD8a is expressed as a heterodimer with CD8b on T cell receptor (TCR) α/β and TCR γ/δ expressing, cytotoxic T cells, and on most thymocytes. As a homodimer of two CD8a chains the CD8 antigen is expressed on most NK cells, a major fraction of intestinal intraepithelial lymphocytes, some activated CD4+CD8+ T cells and CD8+ T cells from athymic rats. CD8a is also expressed by a T cell subset with regulatory functions. | Additional information: Clone REA437 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Johnson, P. et al. (1985) Purification, chain separation and sequence of the MRC OX-8 antigen, a marker of rat cytotoxic T lymphocytes. EMBO J. 4 (10): 2539–2545. | Torres-Nagel, N. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22 (11): 2841–2848. | Strup-Perrot, C. et al. (2005) Expression of matrix metalloproteinases and tissue inhibitor metalloproteinases increases in X-irradiated rat ileum despite the disappearance of CD8a T cells. World J Gastroenterol. 11 (40): 6312–6321.
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CD8a Antibody, anti-rat, Biotin, REAfinity™, 9 µg in 300 µL
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