- 询价
- Miltenyi Biotec
- 德国
- 130-129-860
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD85g (ILT7)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，4-8℃
- 克隆性：
REA100
- 标记物：
APC-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
CD85g (ILT7) Antibody, anti-human, REAfinity™
- 抗体名：
CD85g (ILT7) Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Detection of human CD85g (ILT7)+ cellsThe clone REA100 recognizes human CD85g, also known as immunoglobulin-like transcript 7 (ILT7), a cell surface receptor which is specifically expressed on human plasmacytoid dendritic cells (PDCs). ILT7 associates with FcεR1γ chain through positively charged arginine residue located in the transmembrane domain to form a receptor complex. Cross-linking of ILT7 results in FcεR1γ-dependent activation of an ITAM-mediated signaling pathway, which negatively influences TLR7/9 induced type I IFN production. Cross-linking of ILT7 by REA100 monoclonal antibodies inhibits type I IFN production in human PDCs. | Additional information: Clone REA100 display negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Cao, W. et al. (2006) Plasmacytoiddendritic cell–specific receptor ILT7–FcεRIγ inhibits Toll-like receptor–induced interferon production. J. Exp. Med. 203: 1399–1405.
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CD85g (ILT7) Antibody, anti-human, APC-Vio® 770, REAfinity™, 30 tests in 60 µL
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