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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD83
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA304
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 抗体英文名:
CD83 Antibody, anti-mouse, REAfinity™
- 抗体名:
CD83 Antibody, anti-mouse, REAfinity™
- 规格:
9 µg in 300 µL
Identification and enumeration of CD83+ cells by flow cytometryClone REA304 recognizes the mouse CD83 antigen, a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily. Murine CD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic peptides or T cell receptor-specific monoclonal antibody. When returning to the resting state, T cells down-regulate CD83 again. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of MIDC-8, a known murine DC marker molecule. | Additional information: Clone REA304 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Lüthje, K. et al. (2008) CD83 regulates splenic B cell maturation and peripheral B cell homeostasis. Int. Immunol. 20 (8): 949–960. | Twist, C. J. et al. (1998) The mouse CD83 gene: structure, domain organization, and chromosome localization. Immunogenetics 48 (6): 383–393. | Wolenski, M. et al. (2003) Expression of CD83 in the murine immune system. Med. Microbiol. Immun. 192 (4): 189–192.
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CD83 Antibody, anti-mouse, APC, REAfinity™, 9 µg in 300 µL
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