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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD85k (ILT3)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,4-8℃
- 克隆性:
REA141
- 标记物:
PE-Vio 615
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
CD85k (ILT3) Antibody, anti-human, REAfinity™
- 抗体名:
CD85k (ILT3) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of CD85k (ILT3)+ cells by flow cytometryClone REA141 recognizes CD85k, a member of regulatory immune receptor family, also known as leukocyte immunoglobulin-like receptor (LILRs/LIRs), immunoglobulin-like transcripts (ILTs), or CD85 family. CD85k is a type I membrane protein with two extracellular Ig-like domains, intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIM) and is expressed on monocytes, dendritic cells, and macrophages. In addition, suppressor T cells induce the expression of CD85k on antigen presenting cells. | Additional information: Clone REA141 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Colonna, M. et al. (1997) A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186: 1809–1818. | Cheng, H. et al. (2011) Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): A myeloid inhibitory receptor involved in immune tolerance. J. Biol. Chem. 286: 18013–18025. | Sommer, A. and Fabri, M. (2015) Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells. PLoS One 10 (6): e0130395.
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CD85k (ILT3) Antibody, anti-human, PE-Vio® 615, REAfinity™, 30 tests in 60 µL
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